Traceability for medical measuring devices through optical absorbance liquid filters

Giorgio Brida, Marco Terzi, Mauro Rajteri

Abstract

Many medical measuring devices (MMD), such as those used in clinical diagnostics, use optical absorbance as the measurand. Optical absorbance in MMDs is usually measured in microvolumes, according to pharmaceutical quality standards; some instruments should also be calibrated for absorbance at required specific wavelengths due to their construction. Optical absorbance liquid filters (OALF) are used to calibrate optical absorbance measurement equipment, but there is currently a capability gap across NMIs in the characterization and use of such filters, which leads to a lack of traceability. Currently, precise calibration methods of MMDs for absorbance at required specific wavelengths are not possible using commercially available liquid traceable standards and the calibrations are performed at approximate wavelengths and absorbance levels. This paper describes the take up of traceable measurement capability of absorbance of liquid filters, the assessment of INRiM facility and the progress in the development of new OALF.

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IMEKO-TC8-11-24-2025-026.pdf

DOI

10.21014/tc8-2025.026

IMEKO TC

TC8 - Traceability in Metrology

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